Sciences: Cardiac Systems Biology

Department: Biomedical Engineering

Supervising Faculty Members: Dr. Jeff Saucerman

Specialization: Cardiac Systems Biology

Research Focus: The Cardiac Systems Biology develops computational models and high-throughput cellular experiments to identify and control the biochemical networks that cause heart failure. Lab Website: http://bme.virginia.edu/saucerman/

Job Description: What will students do while they are working for you? Students will work 5-10 hours/week.

The USOAR program focuses on students who have not previously participated in faculty-supervised research. The job description should include tasks that are substantively related to your research activities but should not be so advanced as to overwhelm a student who is new to research work.

The student will work closely with a graduate student to develop novel computer models of the biochemical networks that cause heart failure. These computational models will be used to identify new potential drug targets for heart failure. While these are state-of-the-art models, we have had significant success training undergraduates in these approaches.

Required Skills, Courses, Resources, or Background:  Programming skills; MATLAB, as obtained in BME 2315/3315

Training: BME 2315 (previously listed as BME 3315)- Computational Biomedical Engineering and BME 2104- Cell and Molecular Biology 

What You Will Learn:
By working on this project, students will:

  • Have gained skills in scientific computing
  • Have a much stronger understanding of the molecular causes of heart disease

Gain first-hand experience in how knowledge and tools from their biomedical engineering classes are applied to identify new potential drug targets