Gene
Block
Vice
President and Provost
Unwinding Biological
Clocks
April 12,
2005
UVa Wise Campus
Science Center, Room 100
Wise, VA

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On
the Shelf Michel, S. Geusz, M., Zaritsky, J. and
Block, G. (1993) Circadian rhythm in membrane conductance
expressed in dissociated molluscan neurons. Science 259:
239-241
Block, G.D., Khalsa S., Michel, S. Geusz, M. and McMahon,
D. (1993) Cellular basis of biological timekeeping. Int.
Rev. Cyt. 146: 83-144
Geusz, M., Foster, R., DeGripp, W. and Block, G. (1997)
Opsin-like immunoreactivity in the circadian pacemaker neurons
and photoreceptors of the Bulla eye. Cell Tissue Res. 287:203-210.
Page, T., Fletcher, J. and Block, G. (1997) After-effects
of Entrainment on the Period of the Pacemaker in the Eye
of the Mollusk Bulla gouldiana. J. Biological Rhythm 12:218-225
Khalsa, S. and Block, G. (1997) The role
of Na in the Bulla circadian pacemaker. Chron. Intl. 14:1-8
Herzog, E., Geusz, M., Khalsa, S.B.S.,
Straume, M. and Block, G. (1997) Circadian Rhythms in Mouse
Suprachiasmatic
Nucleus Explants on Multimicroelectrode Plates. Brain Res.
757:285-290.
Herzog, E., Takahashi, J., Block G. (1998) The role of
clock and tissue organization in period determination of
suprachiasmatic nucleus neurons. Nature Neuroscience 1: 708-713
Geusz, M.E., Fletcher, C., Kay, S.A., Block, G.D., Straume,
M., Copeland, N.G., Jenkins, N.A., Day, R.N. (1997) Long-term
monitoring of rhythmic c-fos gene expression from mouse brain
explant cultures. Current Biology 8:758-766.
Michel, M., Manivanan, K., Zaritsky, J., Block, G., (1999)
A delayed rectifier current is modulated by the circadian
pacemaker in Bulla., J. Biol. Rhythms, 14: 141-150
Yamazaki, S., Abe, M., Numano, R., Hida, A., Block, G.,
Sakaki, Y., Tei, H., Menaker M., (2000) Disruption of circadian
organization in jet-lagged transgenic rats. Science, 280:
1599-1603
Herzog, E., Grace, M., Harrer C., Williamson J. and Block,
G. (2000) The effects of the Clock mutation on the developmental
expression of neuropeptides in the suprachiasmatic nucleus,
J. Comp. Neurology, 242: 86-98
Michikazu, A, Herzog, E. and Block, G. (2000) Lithium
lengthens the circadian period of individual suprachiasmatic
nucleus neurons, NeuroReports, 11:3261-3264
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About
the speaker
Gene D. Block, is the chief academic
officer of the University. He is charged with overseeing education,
research,
and public service in all 10 schools of the University, in the University's
libraries
and museums, and in numerous other academically related units of
the University.
In addition to
his role as Vice President and Provost, Mr. Block is the Alumni
Council Thomas Jefferson Professor
in the College of Arts & Sciences. He teaches in the Biology
Department and maintains an NIH-funded research program focused
on the study of biological clocks.
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