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Gene Block
Vice President and Provost

Unwinding Biological Clocks
April 12, 2005
UVa Wise Campus
Science Center, Room 100
Wise, VA


On the web

The University of Virginia serves over one million people every year through more than 400 public service and outreach programs. For more information about outreach at UVa, visit http://www.virginia.edu/outreachvirginia/, an interactive web-based listing of public service programs searchable by region, interest, audience, or type of program.

Some programs you can find in OutreachVirginia database include the following:

Astronomy Public Nights
This program provides over 4000 visitors a year with a chance to observe the stars and planets through the McCormick telescopes and to learn about the research work and history of the observatories.

Faculty Senate Speakers Bureau
The Faculty Senate Speakers Bureau helps community and school groups throughout the Commonwealth identify U.Va. faculty speakers for special events and meetings at no charge. The Speakers Bureau also serves U.Va. alumni clubs throughout the country.

How Things Work: The Physics of Everyday Life
This searchable website encourages everyone to learn about the physics and science of the world around them. Visitors are able to email questions to UVa Professor Lou Bloomfield who posts explanations on the site.

Mountain Lake Biological Station - Summer Courses
Spend the summer taking exciting, hands-on field courses in all areas of biology. Get involved in science in a way you never could on Grounds. Biology lab credit. Financial aid available. Summer courses are open to all qualified applicants.

Netfrog: The Interactive Frog Dissection Tutorial
Award-winning, on-line tutorial designed as a preparation or substitution for laboratory dissection in high school biology classrooms.

Research and Public Service News Archive
A searchable archive of news stories about UVa Research and Public Service.

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On the Shelf

Michel, S. Geusz, M., Zaritsky, J. and Block, G. (1993) Circadian rhythm in membrane conductance expressed in dissociated molluscan neurons. Science 259: 239-241

Block, G.D., Khalsa S., Michel, S. Geusz, M. and McMahon, D. (1993) Cellular basis of biological timekeeping. Int. Rev. Cyt. 146: 83-144

Geusz, M., Foster, R., DeGripp, W. and Block, G. (1997) Opsin-like immunoreactivity in the circadian pacemaker neurons and photoreceptors of the Bulla eye. Cell Tissue Res. 287:203-210.
Page, T., Fletcher, J. and Block, G. (1997) After-effects of Entrainment on the Period of the Pacemaker in the Eye of the Mollusk Bulla gouldiana. J. Biological Rhythm 12:218-225

Khalsa, S. and Block, G. (1997) The role of Na in the Bulla circadian pacemaker. Chron. Intl. 14:1-8

Herzog, E., Geusz, M., Khalsa, S.B.S., Straume, M. and Block, G. (1997) Circadian Rhythms in Mouse Suprachiasmatic Nucleus Explants on Multimicroelectrode Plates. Brain Res. 757:285-290.

Herzog, E., Takahashi, J., Block G. (1998) The role of clock and tissue organization in period determination of suprachiasmatic nucleus neurons. Nature Neuroscience 1: 708-713

Geusz, M.E., Fletcher, C., Kay, S.A., Block, G.D., Straume, M., Copeland, N.G., Jenkins, N.A., Day, R.N. (1997) Long-term monitoring of rhythmic c-fos gene expression from mouse brain explant cultures. Current Biology 8:758-766.

Michel, M., Manivanan, K., Zaritsky, J., Block, G., (1999) A delayed rectifier current is modulated by the circadian pacemaker in Bulla., J. Biol. Rhythms, 14: 141-150

Yamazaki, S., Abe, M., Numano, R., Hida, A., Block, G., Sakaki, Y., Tei, H., Menaker M., (2000) Disruption of circadian organization in jet-lagged transgenic rats. Science, 280: 1599-1603

Herzog, E., Grace, M., Harrer C., Williamson J. and Block, G. (2000) The effects of the Clock mutation on the developmental expression of neuropeptides in the suprachiasmatic nucleus, J. Comp. Neurology, 242: 86-98

Michikazu, A, Herzog, E. and Block, G. (2000) Lithium lengthens the circadian period of individual suprachiasmatic nucleus neurons, NeuroReports, 11:3261-3264

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About the speaker

Gene D. Block, is the chief academic officer of the University. He is charged with overseeing education, research, and public service in all 10 schools of the University, in the University's libraries and museums, and in numerous other academically related units of the University.

In addition to his role as Vice President and Provost, Mr. Block is the Alumni Council Thomas Jefferson Professor in the College of Arts & Sciences. He teaches in the Biology Department and maintains an NIH-funded research program focused on the study of biological clocks.

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