High blood pressure occurs in at least 25 percent of the adult
population and often goes undiagnosed and untreated until a serious
medical problem develops. If left untreated, high blood pressure
can lead to cardiovascular disease, stroke, heart attack and end-stage
kidney disease. U.Va. pathologist Robin A. Felder and colleagues,
armed with a new $1.2 million grant from the NIH's
National Heart, Lung, Blood Institute, will look for a genetic
cause for high blood pressure or the propensity to develop it.
In addition, Felder will study salt-sensitive hypertension to
determine why, in some people, a high salt diet causes elevated
blood pressure, while in others, there is no relationship between
salt intake and blood pressure levels.