All but two of the newer anti-depressant drugs can cause significant sexual dysfunction, according to a study conducted by Dr. Anita H. Clayton, professor and vice chair of U.Va.’s psychiatric medicine department, and Dr. James Pradko, a Michigan primary care physician.

The study included 6,297 patients reporting data to their doctors at 1,101 clinics nationwide. The results were published April 19 in the Journal of Clinical Psychiatry.

The study found that patients taking either Wellbutrin or Serzone had a significantly lower prevalence of sexual dysfunction than patients taking Prozac, Paxil, Zoloft or Effexor. Patients taking Wellbutrin also had significantly fewer sexual problems than patients taking Celexa or Remeron.

(Wellbrutin and Prozac are sold by GlaxoSmithKline, which funded the study.)