People in the Erickson Lab

P.I.

Loren D. Erickson, Ph.D.Loren D. Erickson , Ph.D.
Primary Appointment: Associate Professor of Microbiology
Email Address: lde9w@virginia.edu
Biomedical Sciences Graduate Programs: Microbiology, Immunology and Infectious Diseases, Molecular Medicine, Molecular Cell and Developmental Biology
Member of the Beirne B. Carter Center for Immunology Research

Postdoctoral Fellow

Nekeithia WadeNekeithia S. Wade, Ph.D.
Email Address: nsw6b@virginia.edu
 
 
Research Description: Plasma cells are terminally differentiated B cells which provide humoral protection through the secretion of antibodies. While antibody production is normally beneficial in the clearance of pathogens, this process can become deleterious in autoimmune diseases such as systemic lupus erythematosus (SLE). I study the role of a protein called B cell Maturation Antigen (BCMA) in the regulation of plasma cell differentiation and the development of autoantibodies.
 

Graduate Students

Christine Coquery2013Christine Coquery
Email Address: cmc3ps@virginia.edu
 
Research Description: The generation of long-lived plasma cells, which is necessary for long-lived antibody protection but becomes dysregulated in autoimmune diseases,  initiates in the germinal center.  This process is mediated by a subset of CD4+ T cells known as T Follicular Helper (TFH) cells which themselves are controlled by a subset of regulatory T cells designated T Follicular Regulatory (TFR) Cells. My projects focus on how TFH and TFR cells are regulated and function under normal immune settings and how they become dysregulated in autoimmune disease. 
 
 
 
sssKelly Cox
Email Address: kmc2fa@virginia.edu
 
Research Description: The production of an immune response in response to foreign pathogens is important in our ability to fight off infection. However, the dis-regulation of immunological tolerance can lead to autoimmune disorders such as lupus and rheumatoid arthritis, as well as allergy. I am currently examining the role of B cell maturation antigen in the pathogenesis of allergy.
 

Undergraduate Student

Annelise Bederman
Email Address: agb2np@virginia.edu
 
Research Description: I am currently working on describing the role of the receptor, B Cell Maturation Antigen, in the pathogenesis of diseases including allergy and lupus. My responsibilities include performing ELISAs, immunofluoresence microscopy on tissue samples, and general assistance with ongoing projects in the lab.
 
 

Laboratory Specialist

William Loo 2008William Loo
Email Address: wml2f@virginia.edu
Phone: 982-6452
Research Description: As lab manager, I am responsible for coordinating the research resources used by everyone for experiments. I also assist in experimental design and data acquisition for both the myeloma and lupus projects.