Department of Pharmacology
UVa Health System
P.O. Box 800735
Charlottesville, VA 22908-0735
(434) 924-1919 Fax: (434) 982-3878
The curriculum for each student will be developed with the aid of the graduate committee. During the first year, trainees will rotate through various laboratories in the department and participate in Journal Club. In addition, the following required courses will be taken: BIMS 503 - Macromolecular Structure and Function (Biochemistry), BIMS 812 - Cell Structure and Function, BIMS 832 - Graduate Physiology, and one elective. In the second year, students enroll in BIMS 811 - Gene Structure and Function, PHAR 901 - Human Pharmacology, PHAR 902 - Molecular Characterization of Drug Targets, and one elective.
The program is flexible and with the exception of the required
courses above, other course work will be tailored to the needs and desires of
the individual student. Advanced graduate courses are available in most areas
of pharmacology, as listed above, as well as in allied sciences such as cell
biology, biochemistry, anatomy, physiology, microbiology, and medicinal chemistry.
Most formal courses, with the exception of seminar and Journal Club, will be
completed within the first two years.
Each student is required to present and defend a detailed research
proposal before a faculty committee. This proposition defense is to be completed
by July 1 at the end of the fourth semester.
Research for the dissertation is regarded as the major training of the candidate. An independent research project must be completed and published under the close supervision of an advisor and a thesis committee. The research is started as early as possible in the candidate's program, usually in the second year.
The final examination for the degree of Doctor of Philosophy
is devoted entirely to defense of the dissertation by the candidate.
PHAR 701, 702 - (1) (S)
Seminar in Pharmacology
Recent developments in pharmacology are presented by outside
speakers at weekly intervals to faculty, staff and students. Students participate
by meeting with the speaker for one to two hours during the day of the seminar.
One hour weekly during both the first and second semesters.
PHAR 730 - (7) (Y)
Prerequisite: BIOC 503 and PHY 701.
A lecture course covering the major
fields of pharmacology for medical students. The principal current drugs are
discussed in detail as
prototypes. Emphasizes mechanism of action, drug distribution and biotransformation
in the body, testing new drugs in experimental animals and in the human, and
adverse reactions to drugs and toxicology.
PHAR 811, 812 - (1) (S)
A continuing seminar based on papers in the current literature.
Required participation by departmental staff, fellows, and graduate students.
One hour per week.
PHAR 813, 814 - (1) (IR)
Tutorial in Pharmacology
Students meet for one hour per week with assigned tutors and
discuss, in depth, problems related to pharmacology.
PHAR 897 - (3-12) (S-SS)
Non-Topical Research, Preparation for Research
For masters research,
taken before a thesis director has been selected.
PHAR 898 - (3-12) (S-SS)
For masters thesis, taken under the supervision
of a thesis director.
PHAR 901 - (4) (Y)
Graduate Pharmacology course which provides a knowledge of
systems based drug intervention. Lectures emphasize the pharmacological properties
of drug classes and their use in common human diseases for graduate students.
Discusses major issues associated with the use of these drugs and requires a
familiarity with the assigned materials.
PHAR 902 - (4) (Y)
Molecular Characterization of Drug Targets
Studies the biochemical and molecular aspects of the transmembrane
signaling mechanisms that are known targets for important classes of clinically
useful drugs. Covers potential drug targets in diseases such as cancer. Emphasizes
current knowledge of important signaling mechanisms and examples of the research
leading to the design of important therapeutic agents. A seminar course that
focuses on how an important drug target can be identified and exploited.
PHAR 994 - (3-12) (S-SS)
PHAR 995, 996 - (Credit to be arranged) (S-SS)
Original research on approved problems.
PHAR 997 - (3-12) (S-SS)
Non-Topical Research, Preparation for Doctoral Research
For doctoral research, taken before a dissertation director
has been selected.
PHAR 999 - (3-12) (S-SS)
For doctoral dissertation, taken under the supervision of a