Course Descriptions

BIOL 501 - (4) (Y)
Biochemistry
Prerequisite: CHEM 241, 242 or permission of instructor
The structure and function of the major chemical constituents of cells -- proteins, nucleic acids, lipids and carbohydrates -- and their relationship to cellular metabolism and self-replication. Lectures and discussion.

BIOL 504 - (4) (IR)
Advanced Cell Biology
Prerequisites: BIOL 301 or BIOL 501 and permission of instructor
The structure, development, and function of plant and animal cells as demonstrated by modern studies in molecular biology, cell fine structure, and genetics. Lectures and discussion.

BIOL 505 - (3) (IR)
Temporal Organization of Living Systems
Prerequisites: BIOL 419 or graduate standing
Biological cycles at several levels of organization. Explores both the adaptive significance of biological cycles and the mechanisms that generate them, with emphasis on unanswered questions and unresolved issues.

BIOL 508 - (4) (Y)
Developmental Mechanisms
Prerequisites: BIOL 301 and BIOL 311, or equivalent and BIOL 405 or permission of instructor
An analysis of the cellular and molecular basis of developmental phenomena, reviewing both classical foundations and recent discoveries. Lectures focus on the major developmental systems used for analysis of embryogenesis (for example, mouse, frog and fly) and concentrate on several themes that pervade modern research in this area (e.g., signal transduction mechanisms). Readings are mainly from the primary research literature, but are supplemented by textbook assignments as well. Lectures and discussion.

BIOL 509 - (2) (SI)
Current Topics in Plant Molecular Biology
Prerequisites: BIOL 301 or permission of instructor
A discussion of current literature and selected topics on the biochemical and molecular genetic basis for plant cellular growth and differentiation. Weekly readings and student presentations.

BIOL 512 - (3) (Y)
Comparative Biochemistry
Prerequisites: Organic chemistry, BIOL 301, and permission of instructor
Examination of the biochemical adaptations which have arisen in organisms in response to physiological demands. Topics will be drawn from recent advances made in elucidating molecular mechanisms of metabolic regulation.

BIOL 517 - (3) (SI)
Electronics for Biologists
Prerequisite: Permission of instructor
Consideration of electronics and electronic design for the biologist. Both analog and digital circuits will be covered with emphasis placed on the design of equipment useful for the biological laboratory. One class hour, five laboratory hours.

BIOL 536 - (3) (Y)
Techniques in Light and Electron Microscopy
Prerequisite: Permission of instructor
Topics include elementary theory of light and electron optics, theory and practice of specimen preparation, interpretation of micrographs, scientific photography, and use of specialized techniques such as tracer methods, immunocytochemistry, morphometric analysis, and image enhancement techniques. Laboratory sessions demonstrate techniques and instruments available in the department.

BIOL 540 - (3) (IR)
Sensory Neurobiology
Prerequisite: BIOL 417/817, or the equivalent
In-depth examination of the organization and physiology of the diverse sensory systems found in vertebrate and non-vertebrate animals. The philosophical thrust of the course will focus upon the functional rationale for receptor organization and the manner in which the central nervous system processes incoming sensory information. Visual, auditory, somatosensory, and electrosensory information processing, primarily in vertebrates, will be stressed.

BIOL 701 - (3) (Y)
Evolutionary Biology
Prerequisite: Permission of instructor
This course takes an evolutionary approach to population ecology and ecological genetics. Topics include the principles of natural selection and the evolution of the phenotype, population regulation and life history evolution, mating systems, speciation, and phylogeny reconstruction.

BIOL 711, 712 - (1-4) (Y)
Independent Study in Biology
A member of the faculty of Biology must supervise and approve all components of this course. The student will take and pass one or more courses offered by the Department of Biology at the 300 level or above. In addition, for each course taken, the student will write at least a 10-page paper on a topic relevant to the course. Prior approval of the topic will be obtained from the faculty advisor. The number of credits to be earned will be designated by the faculty advisor prior to enrollment.

BIOL 714 - (4) (IR)
Plant Cell Physiology
Prerequisites: BIOL 301 or permission of instructor
An in-depth analysis of cell structure and metabolic activity during plant cell growth and differentiation. Emphasis is placed on an understanding of the biochemical and molecular genetic factors regulating important plant and cellular physiological activities.

BIOL 723 - (3) (Y)
Animal Physiology
A diversity of examples will be used to identify general principles in physiological adaptation of animals to environmental challenges.

BIOL 747 - (3) (IR)
Light in Biological Systems
Advanced laboratory course providing upper level undergraduate and beginning graduate students with an intensive examination of the role light plays in controlling diverse biological activities. Through a series of laboratory exercises students receive instruction on the theories and principles underlying the detection and measurement of light quality and quantity and the analytical instruments and procedures used to probe structure-function relationships in macromolecules, the effects of light on cellular physiology, and light as a stimulus in controlling behavior. Among the topics covered are absorption and difference spectroscopy, structure and biology of mammalian photoreceptors, action spectra of photoreceptors, UV sensitivity and repair mechanisms, and chromatic adaptation. In addition to preset laboratory exercises, students are required to design and implement their own experiments examining some aspect of photobiology. Additional reading and papers are required for the graduate level course.

BIOL 801 - (2) (Y)
Colloquium in Developmental Biology
Prerequisite: Permission of staff
Student reports covering various aspects of development will be presented for discussion. The direction taken by the course will change each year so that this course may be taken repeatedly for credit. Conference one day a week.

BIOL 802 - (2) (Y)
Colloquium in Physiology
Prerequisite: Permission of staff
Student reports covering various aspects of physiology will be presented for discussion. The direction taken by the course will change each year so that this course may be taken repeatedly for credit. Conference one day a week.

BIOL 803 _ (2) (Y)
Colloquium in Genetics
Prerequisite: Permission of staff
Student reports covering various aspects of genetics will be presented for discussion. The direction taken by the course will change each year so that this course may be taken repeatedly for credit. Conference one day a week.

BIOL 804 - (2) (Y)
Colloquium in Biology
Prerequisite: Permission of staff
In this interdisciplinary course, student reports covering various topics that cross development, genetics, and physiology will be presented for discussion. The direction taken by this course will change each year so that this course may be taken repeatedly for credit. Conference one day a week.

BIOL 805 - (4) (Y)
General and Molecular Genetics
Organization, transmission, function, and regulation of prokaryotic and eukaryotic genes. (This course is cross-listed as MICR 805 and is cooperatively taught with Microbiology staff members.)

BIOL 806 - (2) (IR)
Colloquium in Neurobiology
Prerequisite: BIOL 817 or permission of instructor
Readings and student seminar preparations in neurobiology, usually organized around one coherent topic, which will change from year to year. Course will examine topics of timely experimental and theoretical importance in the areas of membrane physiology, synaptology, simpler neuronal networks, cellular basis of behavior, sensory physiology, and developmental neurobiology. Two hours of seminar presentations.

BIOL 807 - (2) (IR)
Colloquium in Population Biology
Prerequisites: Permission of instructor
The colloquium is arranged around a current topic in population biology. The direction taken by this course will change each year so that this course may be taken repeatedly for credit. Conference one day a week.

BIOL 811 - (5) (Y)
Gene Structure, Expression, and Regulation
A course on the molecular biology of bacterial and eukaryotic cells, with emphasis on the application of recombinant DNA for elucidation of gene structure, the mechanism of gene expression, and its regulation. (Course is cross-listed as MICR 811 and is cooperatively taught with Microbiology staff members.)

BIOL 814 - (2) (SI)
Developmental Genetics
An analysis of the role of genes in development and an examination of the idea of differential gene action during development. Discussion sessions.

BIOL 817 - (4) (Y)
Neurophysiology
Analysis of nerve and muscle function; Nernst and Goldman theories of biological membrane potentials; Hodgkin-Huxley theory of the nerve impulse; passive electrical properties of nerve and muscle membranes; analysis of function in restricted neural networks; mechanisms in neuronal development. Lectures and discussions.

BIOL 820 - (3) (Y)
Structure and Regulation of Eukaryotic Genes
Prerequisite: Permission of instructor
An in-depth discussion of the structure, regulation, and evolution of eukaryotic genes including a review of current literature and ideas in this field.

BIOL 825, 826 - (1) (Y)
Analysis of Current Biological Literature
Oral presentation and analysis of research articles. Required of all first-year graduate students in biology. Presentations.

BIOL 841 - (4) (Y)
Molecular Biology and Genetics
Prerequisite: BIOL 311
The structure and regulation of prokaryotic, eukaryotic and viral genes are examined at the molecular level. Experimental approaches in molecular biology that address mechanisms of replication, transcription, RNA processing and translation are emphasized. Discussion of current advances in genetic research. Three lecture hours and one hour discussion section.

BIOL 849 - (2) (IR)
Advanced Drosophila Genetics
Prerequisite: BIOL 311 or equivalent
Examines the repertoire of sophisticated genetic techniques available in Drosophila. Topics covered include: segregation and use of translocation heterozygotes in the generation of segmental anueploids; segregation and use of compound chromosomes including their use in the half-tetrad analysis of gene conversion events; a survey of the large variety of methods for making mosaics; methods for P-element induced mutagenesis including site directed mutagenesis; P-element mediated transformation; the use of enhancer traps.

BIOL 880 - (2) (SI)
Selected Topics in Genetics
Reports from the recent literature on the nature of the gene and gene action. Conference one day a week.

BIOL 881 - (2) (SI)
Selected Topics in Evolution
Prerequisite: Permission of instructor
A study of current problems in the evolution of living organisms with reviews of the recent literature. Conference one day a week.

BIOL 882 - (2) (SI)
Selected Topics in Developmental Biology
Prerequisite: Permission of instructor
A discussion of current problems.

BIOL 884 - (2) (SI)
Selected Topics in Physiology
A discussion of current problems.

BIOL 885 - (2) (SI)
Selected Topics in Molecular Genetics
A seminar on current problems in molecular genetics with reports from the recent literature. Conference one day a week.

BIOL 886 - (2) (SI)
Selected Topics in Cell Biology
Prerequisite: Permission of instructor
A discussion of current problems.

BIOL 887 - (2) (SI)
Selected Topics in Developmental Genetics
Prerequisite: Permission of instructor
A discussion of current problems.

BIOL 888 - (2) (SI)
Selected Topics in Biochemistry
Prerequisite: Permission of instructor
A discussion of current problems.

BIOL 890 - (3) (SI)
Selected Topics in Developmental Botany
Prerequisite: Permission of instructor
A discussion of current problems.

BIOL 897 - (3-12) (S)
Non-Topical Research, Preparation for Research
For master's research, taken before a thesis director has been selected.

BIOL 898 - (3-12) (S)
Non-Topical Research
For master's thesis, taken under the supervision of a thesis director.

BIOL 901, 902 - (1-12) (S)
Research in Genetic Development

BIOL 903, 904 - (1-12) (S)
Research in Yeast Genetics

BIOL 905, 906 - (1-12) (S)
Research in Population Studies

BIOL 907, 908 - (1-12) (S)
Research in Molecular Genetics

BIOL 909, 910 - (1-12) (S)
Research in Developmental Biology

BIOL 911, 912 - (1-12) (S)
Research on Protein Structure

BIOL 913, 914 - (1-12) (S)
Research in Bacteriophage Biochemistry

BIOL 915, 916 - (1-12) (S)
Research in Biochemistry

BIOL 917, 918 - (1-12) (S)
Research in Genetics

BIOL 923, 924 - (1-12) (S)
Research in Neuroethology of Electric Fish

BIOL 925, 926 - (1-12) (S)
Research in Population Biology

BIOL 927, 928 - (1-12) (S)
Research in Plant Physiology

BIOL 929, 930 - (1-12) (S)
Research in Plant Biology

BIOL 933, 934 - (1-12) (S)
Research in the Circadian Organization of Vertebrates

BIOL 935, 936 - (1-12) (S)
Research in Cell Structure and Function

BIOL 937, 938 - (1-12) (S)
Research in Gene Expression During Development

BIOL 939, 940 - (1-12) (S)
Research in Behavior Neuroendocrinology

BIOL 943, 944 - (1-12) (S)
Research in General Physiology

BIOL 945, 946 - (1-12) (S)
Research in Evolutionary Biology

BIOL 947, 948 - (1-12) (S)
Research in Neurophysiology and Developmental Neurobiology

BIOL 951, 952 - (1-12) (S)
Research in Cell Structure and Function

BIOL 955, 956 - (1-12) (S)
Research in Invertebrate Development

BIOL 961, 962 - (1-12) (S)
Research in Cell Biology

BIOL 963, 964 - (1-12) (S)
Research in Drosophila Neurobiology

BIOL 965, 966 - (1-12) (S)
Research in Ecological Genetics

BIOL 967, 968 - (1-12) (S)
Research in Animal Cell Growth

BIOL 973, 974 - (1-12) (S)
Research in Animal Behavior

BIOL 975, 976 - (1-12) (S)
Research in Human Genetics

BIOL 977, 978 - (1-12) (S)
Research in Molecular Aspects of Development

BIOL 979, 980 - (1-12) (S)
Research in Development and Function of Neuronal Networks

BIOL 981, 982 - (1-12) (S)
Research in Developmental Genetics and Morphogenesis

BIOL 983, 984 - (1-12) (S)
Research in the Neurophysiological Basis of Circadian Rhythms

BIOL 991, 992 - (4) (Y)
Rotation Research
Required of all first-year graduate students in biology.

BIOL 996 - (1-12) (S)
Research

BIOL 997 - (1-12) (S)
Non-Topical Research, Preparation for Doctoral Research
For doctoral research, taken before a dissertation director has been selected.

BIOL 999 - (1-12) (S)
Non-Topical Research
For doctoral dissertation, taken under the supervision of a dissertation director.

Continue to: Departmental Degree Requirements
Return to: Chapter 5 Index