Patent Foundation Announces Inventor of the Year
Dr. Joel Linden,
Prolific Inventor And Entrepreneur, Recognized For Developing Agent
That Reduces Swelling
April 10, 2002-- The University
of Virginia Patent Foundation has named Dr. Joel Linden the Edlich-Henderson
Inventor of the Year for his work in developing a family of anti-inflammatory
compounds that may avert paralysis in some patients with spinal
his compounds cannot restore nerve connections for patients whose
spinal cords have been severed, early tests show they can reduce
the inflammation that damages surrounding tissue, which can cause
paralysis as a secondary result of injury, said Robert MacWright,
executive director of the U.Va. Patent Foundation.
the past four years, Linden, a professor of cardiovascular medicine,
molecular physiology and biological physics at U.Va., has collaborated
with Timothy MacDonald, chair of the chemistry department, to develop
a number of new compounds that activate the bodys adenosine
receptors -- A2A compounds and stop tissue damage due to
swelling. In addition to spinal cord injuries, the anti-inflammatory
compounds also may reduce tissue damage from loss of blood flow
during heart surgery or organ transplants.
Linden is one of U.Va.s most prolific inventors and a pioneering
faculty entrepreneur," MacWright said. "We are pleased
to recognize his important contribution in demonstrating that adenosine
analogs can act as anti-inflammatory agents, and to recognize his
even broader contributions toward the Patent Foundations goal
of seeing that U.Va. inventions benefit the public."
U.Va. Patent Foundation Award recognizes an invention with strong
commercial potential and notable value to society. The invention
may be used in treating disease, protecting the environment, in
research or education, or in helping the disadvantaged, the disabled
and the elderly.
research at U.Va. has been supported by the National Institutes
of Health and through private funding from his biotech start-up
company, Adenosine Therapeutics. Adenosine is in negotiations with
several major drug companies to develop and test new drugs based
on the results of his research.
winners of the U.Va. Inventor of the Year Award are:
2001 Doris Kuhlmann-Wilsdorf
2000 -- Ron Taylor
1999 -- John Herr
1998 Not awarded
1997 -- Richard Guerrant and Timothy MacDonald
Inventor of the Year Award was the brainchild of Dr. Richard Edlich,
U.Va. professor emeritus and currently editor-in-chief of the Journal
of Long-Term Effects of Medical Implants.
J. Henderson, president and chief financial officer of Robbins &
Henderson, a New York firm specializing in financial and related
services for institutions, has been active in promoting partnerships
between universities and industry.
U.Va. Patent Foundation is a not-for-profit Virginia corporation
with the University of Virginia that promotes the transfer of technology
developed at the University to business and industry, so that products
and therapies based on U.Va. research can directly benefit the public.
Joanna Gluckman, (434) 924-6858