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Michael
Menaker Named By Governor As Outstanding Scientist Of 2003
February 11, 2003--
Gov. Mark R. Warner and Science Museum of Virginia Director
Dr. Walter R.T. Witschey yesterday announced that Michael Menaker,
Commonwealth Professor of Biology, is one of eight Outstanding Scientists
and Industrialists of 2003. The awardees include six university
scientists and two corporate chief executive officers. They will
be introduced to the General Assembly on Feb. 18 and receive their
awards at a banquet at the Science Museum in Richmond on April 1.
"These
recipients are at the cutting edge of their fields," said Gov.
Warner. "Their creativity, contributions, and dedication are
aimed at making life - in Virginia and beyond - better for us all."
Menaker's
research focuses on circadian clocks - the internal timers that
regulate rhythmic behaviors and functions of organs. Menaker’s
laboratory has provided the best evidence that a specific part of
the brain is the “master clock” regulating the activity-rest
cycle in mammals, and that this clock is synchronized to day and
night by special photoreceptors (light sensing cells) in the eyes
that are not used for image formation. These cells have recently
been identified by other laboratories as a completely novel set
of photoreceptors in the retina that are likely to be important
to normal synchrony of humans.
Menaker’s
lab has discovered circadian clocks in most peripheral organs, such
as the lung and liver, and are investigating the way these clocks
interact with the master clock in the brain and with the environment
to control organ function.
Research
in biological timing has implications for many areas of human life,
from jet lag to shift work. A better understanding of the internal
clock could reduce accidents due to fatigue. Researchers also are
investigating ways to deliver drug treatments for cancer and other
diseases, timed to the peak rhythms of body clocks. This new area,
chronopharmacology, holds promise for more effective treatment of
emotional disorders, hypertension, cancer and insomnia.
For
more on Menaker’s research, check the following Web links:
http://www.virginia.edu/insideuva/2002/11/bio_timing.html
http://www.virginia.edu/insideuva/2002/25/master_clock.html
http://www.virginia.edu/insideuva/2001/04/jetlag.html
http://www.virginia.edu/insideuva/2000/16/jetlag.html
Contact:
Fariss Samarrai, (434) 924-3778
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