RELEASE ON RECEIPT Reporters, Editors: Dr. Daniel and Dr. Truwit will be available on Wednesday, April 26, from 1:30 to 2:30 p.m. to explain the procedure. A patient from Lynchburg who has benefitted from the surgery also will be available. Please contact Marguerite Beck at 804-924-5679 if you will be attending the briefing. Contact: Marguerite Beck U.VA. SURGEONS OFFER NEW TREATMENT FOR EMPHYSEMA CHARLOTTESVILLE, VA., April 21 -- A new surgical treatment for emphysema is being performed at the University of Virginia Medical Center. Until recently, there has been no surgical treatment available except lung transplants for the more than a million people who suffer from this deadly form of lung disease. Lung shaving, or lung-volume reduction surgery, was first used as a treatment for emphysema about a year-and-a-half ago by Dr. Joel D. Cooper at Washington University School of Medicine in St. Louis. A surgical team headed by Dr. Thomas Daniel and Dr. Jonathon Truwit has been performing the surgery at U.Va. since May 1994. In properly selected patients, the results have been dramatic, with about 85 percent showing marked improvement in breathing capacity, according to Daniel, professor of surgery at U.Va. Emphysema occurs when the alveoli -- microscopic air sacs in the lungs by which oxygen is added to the blood and carbon dioxide is removed from it -- lose their natural elasticity, become overstretched and rupture. In time, this process causes the lungs to overinflate, creating the characteristic barrel chest associated with emphysema patients. "We know there is more to breathing than just the lungs -- the diaphragm motion is what moves the air in and out," Daniel said. "With emphysema, the diseased lungs are hyperexpanded much like an over-inflated balloon. This hyperexpansion makes it difficult for the person to properly use the diaphragm or intercostal muscles -- the muscles along the rib cage -- that facilitate breathing. "Removing a small portion of the lungs reduces the overall size, which may help the patient obtain more diaphragm or bellows motion so breathing is easier and more effective." The lung shaving procedure involves making an incision across the sternum or breastbone -- much like in a heart operation -- to gain access to both lungs at the same time. The surgeon then shaves or cuts off about 20 percent of the outside of each lung, decreasing the over-expansion of the lung and allowing the patient to breathe in and out more effectively. Although the surgical technique is not that difficult, Daniel said success depends on the ability to determine who will make the best candidate for the procedure and how much and what part of the lung to remove. At U.Va., a careful patient selection process, developed by Daniel and Truwit, is followed and pre- and post- operative therapy are mandatory. Once a patient has been selected for surgery, the real work begins. Each patient must participate in an intensive chest physiotherapy program for six weeks, including workouts on a treadmill five times a week. "Patients prepare for surgery like they are preparing for the Super Bowl," Daniel said. "With emphysema, the person's whole body is absorbed in trying to stay alive by breathing. People lose weight and their breathing is often so labored that they can't even speak in full sentences. So we spend a great deal of time and effort trying to reverse the ravages of the disease before surgery to improve the outcome." After surgery, patients are involved in another six-week intensive therapy program to teach them how to breathe properly again and increase their muscle strength and endurance. Daniel said that U.Va. is developing rehabilitation facilities and a hospital unit with specially trained nurses and physical therapists to offer pre- and post-operative care for patients treated with the lung shaving procedure. Currently, U.Va. is using the Martha Jefferson Hospital outpatient rehabilitation center for the pre- and post-operative physical therapy. The procedure currently is covered by Medicare and Blue Cross/Blue Shield. The lung shaving procedure costs about $35,000 whereas a lung transplant costs approximately $150,000 plus the lifetime cost of medication to prevent rejection. ### April 21, 1995