EXAMINATION OF METEORITE SUGGESTS EXTRATERRESTRIAL HAND IN ORIGIN OF LIFE ON EARTH CHARLOTTESVILLE, Va., Sept. 16 -- Geochemists from the universities of Virginia and Oklahoma who examined a meteorite that fell in Australia in 1969 have found evidence bolstering a theory that the origin of life on Earth may have been shaped by extraterrestrial influences. Writing in the Sept.18 issue of the prestigious British journal Nature, University of Oklahoma professor Michael H. Engel and University of Virginia professor Stephen A. Macko present new supporting evidence that extraterrestrial material which bombarded our planet more than 4 billion years ago contained amino acids with characteristics similar to those observed in all living systems on Earth. Engel had published similar findings in 1982, but questions arose as to whether the meteorite carried the amino acids with it or if it had been "contaminated" by earthly influences after it landed. However, using a state-of-the-art lab at the University of Virginia, Engel and Macko found that the amino acids on the meteorite contained a much greater concentration of a particular nitrogen isotope than naturally occurs on Earth, confirming the extraterrestrial origin of the amino acids. "This has great importance to understanding the origin of the chemical precursors to life," said Macko, a professor in U.Va.'s environmental sciences department. Most amino acids - the building blocks of life - come in two types: "left-handed" (L) and "right-handed" (D). Living systems must be based on only one of those types. On Earth, the left handed amino acids were selected. Engel and Macko's work supports one theory of how the left-handed amino acids came to dominate. The non-biological synthesis of amino acids on the very early Earth is assumed to have OVER resulted in the formation of L- and D-type molecules in equal quantities. But organic compounds, including amino acids, are also known to have been delivered by comet and meteorite impacts - in large quantities at the time of life's origins on Earth, and in smaller quantities even today. The Murchison meteorite which landed in Australia in 1969 was found to be rich in amino acids, and Engel's earlier work found that they were predominately of the left-handed variety. At the time, this was touted as evidence that extraterrestrial material may have tipped the balance of amino acids on Earth toward the left-handed variety during the critical window for life's origin, about 4 billion years ago. But questions arose as to the source of the material on the Murchison meteorite, including the possibility of contamination by earthly biological material during or after impact. Engel and Macko's current study may put those doubts to rest, confirming that the excess of L-type amino acids on the Murchison meteorite can indeed be traced to extraterrestrial origins. Using Macko's lab at U.Va. to measure the nitrogen isotopes in the Murchison amino acids, they became the first in the world to measure amounts of "heavy" nitrogen (nitrogen-15) on extraterrestrial objects that are clearly in excess of that observed for amino acids in living systems on Earth today. "This is one of the unique facilities in the world for doing this," said Macko, who said there are only a handful of other labs which have the capability of measuring levels of nitrogen-15 and an isotope of carbon, carbon-13, on individual compounds. ### September 15, 1997 For more information, contact Stephen A. Macko at (804) 924-7761 or via e-mail at sam8f@virginia.edu; or Michael Engel at (405) 325-4435 or via e-mail at ab1635@uokmvsa.backbone.uoknor.edu. Television reporters may contact the U.Va. TV News Office at (804) 924-7550. Please note that Engel and Macko will be out of the country for a conference in late September. From Sept. 21-26, Macko may be reached in the Netherlands at the Hotel Bergere in Maastricht, phone 43-325-1651. On Sept. 20, Engel will be at the Ramada Hotel Gatwick outside of London, phone 44-1293 820-169. From Sept. 21-26, Engel may be reached at Barbizon Maastricht, phone 43-383-8281.